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Lequyer, J., Philip, R., Sharma A., Hsu, W.-H., Pelletier, L. (2022). A fast blind zero-shot denoiser. Nature Mach Intell. doi: https://doi.org/10.1038/s42256-022-00547-8
Prosser, S. L., Tkach, J., Gheiratmand, L., Kim, J., Raught, B., Morrison, C. G., & Pelletier, L. (2022). Aggresome assembly at the centrosome is driven by CP110–CEP97–CEP290 and centriolar satellites. Nature Cell Biology, 24(4), 483–496. doi: https://doi.org/10.1038/s41556-022-00869-0
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Park, K., Li, C., Tsiropoulou, S., Gonçalves, J., Kondratev, C., Pelletier, L., … Leroux, M. R. (2021). CDKL kinase regulates the length of the ciliary proximal segment. Current Biology, 31(11), 2359-2373.e7. doi: https://doi.org/10.1016/j.cub.2021.03.068
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Devi, R., Pelletier, L., & Prosser, S. L. (2021). Charting the complex composite nature of centrosomes, primary cilia and centriolar satellites. Current Opinion in Structural Biology, 66, 32–40. doi: https://doi.org/10.1016/j.sbi.2020.10.006
Tsatskis Y., Rosenfeld R., Pearson J. D., Boswell C., Qu Y., Kim K., … McNeill H. (2020). The NEMP family supports metazoan fertility and nuclear envelope stiffness. Science Advances, 6(35), eabb4591. doi: https://doi.org/110.1126/sciadv.abb4591
Gonçalves J., Sharma A., Coyaud É., Laurent E., Raught B., & Pelletier L., LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation. Journal of Cell Biology, 219(7). June 4 (2020). PMID: 32496561
Liu Y., Kim J., Philip R., Sridhar V., Chandrashekhar M., Moffat J., van Breugel M., & Pelletier L., Direct interaction between CEP85 and STIL mediates PLK4-driven directed cell migration. Journal of Cell Science, 133(8), jcs238352. April 23 (2020). doi: https://doi.org/10.1242/jcs.238352
Aynaud M.M., Hernandez J., Barutcu S., Braunschweig U., Chan K., Pearson J., Trcka D., Prosser S., Kim J., Barrios-Rodiles M., Jen M., Song S., Shen J., Bruce C., Hazlett B., Poutanen S., Attisano L., Bremner R., Blencowe B., Mazzulli T., Han H., Pelletier L., & Wrana J., A Multiplexed, Next Generation Sequencing Platform for High-Throughput Detection of SARS-CoV-2. medRxiv. October 20 (2020). doi: https://doi.org/10.1101/2020.10.15.20212712
Pearson J., Trcka D., Hyduk S., Aynaud M.M., Hernández J., Peidis F., Lu S., Chan K., Woodgett J., Mazzulli T., Attisano L., Pelletier L., Cybulsky M., Wrana J., & Bremner R., Comparison of SARS-CoV-2 Indirect and Direct Detection Methods. bioRxiv. May 13 (2020). doi: https://doi.org/10.1101/2020.05.12.092387
Prosser S., & Pelletier L., Centriolar satellite biogenesis and function in vertebrate cells. Journal of Cell Science, 133(1). Jan 2 (2020). PMID: 31896603
Gheiratmand L., Coyaud E., Gupta G., Laurent E., Hasegan M., Prosser S., Gonçalves J., Raught B., & Pelletier L., Spatial and proteomic profiling reveals centrosome-independent features of centriolar satellites. The EMBO Journal, 38(14), e101109. (2019). PMID: 31304627
Luo Y., Barrios-Rodiles M., Gupta G., Zhang Y., Ogunjimi A., Bashkurov M., Tkach J., Underhill A., Zhang L., Bourmoum M., Wrana J. & Pelletier L., Atypical function of a centrosomal module in WNT signalling drives contextual cancer cell motility. Nature Communications, 10(1). May 29 (2019). PMID: 31142743
Lambert J.P., Picaud S., Fujisawa T., Hou H., Savitsky P., Uusküla-Reimand L., Gupta G.D., Abdouni H., Lin Z.Y., Tucholska M., Knight J.D.R., Gonzalez-Badillo B., St-Denis N., Newman J.A., Stucki M., Pelletier L., Bandeira N., Wilson M.D., Filippakopoulos P., Gingras A.C., Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Mol Cell. Feb 7 (2019). PMID: 30554943
Liu Y., Pelletier L., A magic bullet for targeting cancers with supernumerary centrosomes. EMBO J Jan 15 (2019). PMID: 30538103
Go C., Knight J., Rajasekharan A., Rathod B., Hesketh G., Abe K., Youn J.Y., Samavarchi-Tehrani P., Zhang H., Zhu L., Popiel E., Lambert J.P., Coyaud É., Cheung, S., Rajendran, D., Wong, C., Antonicka, H., Pelletier, L., Raught, B., Palazzo A., Shoubridge E., & Gingras A.C., A proximity biotinylation map of a human cell. bioRxiv October 07 (2019). doi: https://doi.org/10.1101/79639
Gonçalves J., Coyaud É., Laurent,E., Raught B., & Pelletier L., LUZP1 and the tumour suppressor EPLIN are negative regulators of primary cilia formation. bioRxiv August 15 (2019). doi: https://doi.org/10.1101/736389
Coyaud É., Ranadheera C., Cheng D.T., Gonçalves J., Dyskov B., Laurent E., St-Germain J.R., Pelletier L., Gingras A.C., Brumell J.H., Kim P.K., Safronetz D., Raught B., Global interactomics uncovers extensive organellar targeting by Zika virus. Mol Cell Proteomics Jul 23 (2018). PMID: 30037810
Liu Y., Gupta G.D., Barnabas D.D., Agircan F.G., Mehmood S., Wu D., Coyaud É., Johnson C.M., McLaughlin S.H., Andreeva A., Freund S.M.V., Robinson C.V., Cheung S.W.T., Raught B., Pelletier L., van Breugel M., Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly. Nat. Commun. Apr 30 (2018). PMID: 29712910
Canning P., Park K., Gonçalves J., Li C., Howard C.J., Sharpe T.D., Holt L.J., Pelletier L., Bullock A.N., Leroux M.R., CDKL family kinases have evolved distinct structural features and ciliary function. Cell Rep. Jan 23 (2018). PMID: 29420175
Gupta G.D., Pelletier L., Centrosome biology: polymer-based centrosome maturation.. Curr Biol. Sept 11 (2017). PMID: 28898644
Knight J.D.R., Choi H., Gupta G.D., Pelletier L., Raught B., Nesvizhskii A.I., Gingras A.C., ProHits-viz: a suite of web tools for visualizing interaction proteomics data. Nat Meth. June 29 (2017). PMID: 28661499
Mojarad B.A., Gupta G.D., Hasegan M., Goudiam O., Basto R., Gingras A.C., Pelletier L., CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme. Open Biology. June 7 (2017). PMID: 28659385
Gonçalves J., Pelletier L., The ciliary transition zone: finding the pieces and assembling gate. Mol Cells Apr 12 (2017). PMID: 28401750
Prosser S.L., Pelletier L., Mitotic spindle assembly in animal cells: a fine balancing act. Nat Rev Mol Cell Biol. Mar 18 (2017). PMID: 28174430
St-Denis N., Gupta G.D., Lin Z.Y., Gonzalez-Badillo B., Veri A.O., Knight J.D., Rajendran D., Couzens A.L., Currie K.W., Tkach J.M., Cheung S.W., Pelletier L., Gingras A.C., Phenotypic and interaction profiling of the human phosphatases identifies diverse mitotic regulators. Cell Rep. Nov 22 (2016). PMID: 27880917
Durocher D., Pelletier L., 53BP1 goes back to its p53 roots. Mol Cell. Oct 6 (2016). PMID: 27716486
Strecker J., Gupta G.D., Zhang W., Bashkurov M., Landry M.C., Pelletier L., Durocher D., DNA damage signalling targets the kinetochore to promote chromatin mobility. Nat Cell Biol. Mar 18 (2016). PMID: 26829389
Gupta G.D., Coyaud É., Gonçalves J., Mojarad B.A., Liu Y., Wu Q., Gheiratmand L., Comartin D., Tkach J.M., Cheung S.W., Bashkurov M., Hasegan M., Knight J.D., Lin Z.Y., Schueler M., Hildebrandt F., Moffat J., Gingras A.C., Raught B., Pelletier L., A dynamic protein interaction landscape of the human centrosome-cilium interface. Cell Dec 3 (2015). PMID: 26638075
Yeh C., Coyaud É., Bashkurov M., van der Lelij P., Cheung S., Peters J.M., Raught B., Pelletier L., The deubiquitinase USP37 regulates chromosome cohesion and mitotic progression. Curr Biol. Aug 31 (2015). PMID: 26299517
Prosser S.L., Pelletier L., Centrosome Biology: The Ins and outs of centrosome assembly. Curr Biol. Aug 3 (2015). PMID: 26241140
Antonczak A.K., Mullee L.I., Wang Y., Comartin D., Inoue T., Pelletier L., Morrison C.G., Opposing effects of pericentrin and microcephalin on the pericentriolar material regulate CHK1 activation in the DNA damage response. Oncogene July 13 (2015). PMID: 26165835
St-Denis N., Gupta G.D., Lin Z.Y., Gonzalez-Badillo B., Pelletier L., Gingras A.C., Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission. Mol Cell Proteomics. Apr 14 (2015). PMID: 25659891
Prosser S.L., Sahota N.K., Pelletier L., Morrison C. G., Fry A.M., Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis. J Cell Biol. May 11 (2015). PMID: 25963817
Luo Y., Pelletier L., Pericentrin: critical for spindle orientation. Curr Biol. Oct 6 (2014). PMID: 25291638
Truong D., Brabant D., Bashkurov M., Wan L.C., Braun V., Heo W.D., Meyer T., Pelletier L., Copeland J., Brumell J.H., Formin-mediated actin polymerization promotes Salmonella invasion. Cell Microbiol. July 21 (2013). PMID: 23869992
Comartin D., Gupta G.D., Fussner E., Coyaud E., Hasegan M., Archinti M., Cheung S.W., Pinchev D., Lawo S., Raught B., Bazett-Jones D.P., Lüders J., Pelletier L., CEP120 and SPICE1 Cooperate with CPAP in Centriole Elongation. Curr Biol. July 22; 23(14):1360-6 (2013). PMID: 23810536
Ernst A., Avvakumov G., Tong J., Fan Y., Zhao Y., Alberts P., Persaud A., Walker J.R., Neculai A.M., Neculai D., Vorobyov A., Garg P., Beatty L., Chan P.K., Juang Y.C., Landry M.C., Yeh C., Zeqiraj E., Karamboulas K., Allali-Hassani A., Vedadi M., Tyers M., Moffat J., Sicheri F., Pelletier L., Durocher D., Raught B., Rotin D., Yang J., Moran M.F., Dhe-Paganon S., Sidhu S.S., A strategy for modulation of enzymes in the ubiquitin system. Science Feb 1;339(6119):590-5(2013). PMID: 23287719
Lawo S., Hasegan M., Gupta G.D., Pelletier L., Subdiffraction imaging of centrosomes reveals higher-order organizational features of pericentriolar material. Nat Cell Biol. October 21 (2012). PMID: 23086237
Canton D., Keene C., Swinney K., Langeberg L., Nguyen V., Pelletier L., Pawson T., Wordeman L., Stella N., Scott J., Gravin Is a Transitory Effector of Polo-like Kinase 1 during Cell Division. Mol Cell October 9 (2012). PMID: 23063527
Gomez-Ferreria M.A., Bashkurov M., Mullin M., Gingras A.C., Pelletier L., CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly. Cell Cycle Aug 16;11(19) (2012). PMID: 22895009
Pelletier L., Yamashita Y.M., Centrosome asymmetry and inheritance during animal development. Curr Opin Cell Biol. Aug;24(4):541-6 (2012). PMID: 22683192
Gomez-Ferreria M., Bashkurov M., Helbig A., Larsen B., Pawson T., Gingras A.C., Pelletier L., Novel NEDD1 phosphorylation sites regulate gamma-tubulin bindingand mitotic spindle assembly. J Cell Sci. Aug 15 (2012). PMID: 22595525
Al-Hakim A.K., Bashkurov M., Gingras A.C., Durocher D., Pelletier L., Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture. Mol Cell Proteomics Jun;11(6):M111.014233 (2012). PMID: 22261722
Kaniuk N.A., Canadien V., Bagshaw R.D., Bakowski M., Braun V., Landekic M., Mitra S., Huang J., Heo W.D., Meyer T., Pelletier L., Andrews-Polymenis H., McClelland M., Pawson T., Grinstein S., Brumell J.H., Salmonella exploits Arl8B-directed kinesin activity to promote endosome tubulation and cell-to-cell transfer. Cell Microbiol. Nov;13(11):1812-23 (2011). PMID: 21824248
Kean M.J., Ceccarelli D.F., Goudreault M., Sanches M., Tate S., Larsen B., Gibson L.C., Derry W.B., Scott I.C. Pelletier L., Baillie G.S., Sicheri F., Gingras A.C., Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization. J Biol Chem. Jul 15;286(28):25065-75 (2011). PMID: 21561862
Gomez-Ferreria M., Pelletier L., Centrosome biogenesis: centrosomin sizes things up! Curr Biol. Dec 21;20(24):R1069-71 (2010) PMID: 21172623
Hutchins J.R., Toyoda Y., Hegemann B., Poser I., Hériché J.K., Sykora M.M., Augsburg M., Hudecz O., Buschhorn B.A., Bulkescher J., Conrad C., Comartin D., Schleiffer A., Sarov M., Pozniakovsky A., Slabicki M.M., Schloissnig S., Steinmacher I., Leuschner M., Ssykor A., Lawo S., Pelletier L., Stark H., Nasmyth K., Ellenberg J., Durbin R., Buchholz F., Mechtler K., Hyman A.A., Peters J.M., Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science Apr 30;328(5978):593-9 (2010). PMID: 20360068
Lawo S., Bashkurov M., Mullin M., Ferreria M.G., Kittler R., Habermann B., Tagliaferro A., Poser I., Hutchins J.R., Hegemann B., Pinchev D., Buchholz F., Peters J.M., Hyman A.A., Gingras A.C., Pelletier L., HAUS, the 8-Subunit Human Augmin Complex, Regulates Centrosome and Spindle Integrity. Curr Biol. May 26;19(10):816-26 (2009). PMID: 19427217
Stewart G.S., Panier S., Townsend K., Al-Hakim A.K., Kolas N.K., Miller E.S., Nakada S., Ylanko J., Olivarius S., Mendez M., Oldreive C., Wildenhain J., Tagliaferro A., Pelletier L., Taubenheim N., Durandy A., Byrd P.J., Stankovic T., Taylor A.M., Durocher D., The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell Feb 6;136(3):420-34 (2009).PMID: 19203578
Pelletier L., Centrosomes: Keeping Tumors in Check. Curr. Biol. Aug 26;18(16):R702-4. (2008). PMID: 18727904
Kittler R., Pelletier L., Buchholz F., Systems biology of mammalian cell division. Cell Cycle Jul;7(14):2123-8. (2008). PMID: 18635956
Poser I., Sarov M., Hutchins J.R., Hrich J.K., Toyoda Y., Pozniakovsky A., Weigl D., Nitzsche A., Hegemann B., Bird A.W., Pelletier L., Kittler R., Hua S., Naumann R., Augsburg M., Sykora M.M., Hofemeister H., Zhang Y., Nasmyth K., White K.P., Dietzel S., Mechtler K., Durbin R., Stewart A.F., Peters J.M., Buchholz F., Hyman A.A., BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Meth. May;5(5):409-15. (2008). PMID: 18391959
Zhu F.*, Lawo S.*, Bird A., Pinchev D., Ralph A., Richter C., Müller-Reicher T., Kittler R., Hyman A., Pelletier L., Cep192 regulates centrosome biogenesis in mammalian cells. Curr Biol. 18(2):136-41) (2008). *Joint-first authors. PMID: 18207742
Kolas N., Chapman J.R., Nakada S., Ylanko J., Chahwan R., Sweeney F.D., Panier S., Mendez Wildenhain J.M., Thomson T.M., Pelletier L., Jackson S.P., Durocher D., Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 318(5856):1637-40 (2007). PMID: 18006705
Pelletier L., Centrioles: Duplicating Precariously. Curr Biol Sep 4;17(17):R770-3.) 2007. PMID: 17803930
Kittler R.*, Pelletier L*, Heninger A., Slabicki M., Theis M., Miroslaw L., Poser I., Lawo S., Grabner S., Kozak K., Wagner J., Surendranath V., Richter C., Bowen W., Jackson A.L., Habermann B., Hyman A.A., Buchholz F., Genome-wide RNAi profiling of cell cycle progression in human tissue culture cells. Nat Cell Biol. 9(12):1401-1412 (2007). *Joint-first authors. PMID: 17994010
Pelletier L., O’Toole E.T., Schwager A., Hyman A.A., Müller-Reichert T., Centriole assembly in Caenorhabditis elegans. Nature, 444 (7119):619-23 (2006). PMID: 17136092
Riedel C.G., Katis V.L., Katou Y., Mori S., Itoh T., Helmhart W., Galova M., Petronczki M., Gregan J., Cetin B., Mudrak I., Ogris E., Mechtler K., Pelletier L., Buchholz F., Shirahige K., Nasmyth K., Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature 441(7089):53-61 (2006). PMID: 16541024
Hartmann J., Hu K., He C.Y., Pelletier L., Murray J.M., Roos D.S., Warren G., Golgi and centrosome cycles in Toxoplasma gondii. Molecular & Biochemical Parasitology 1(145):125-127 (2006). PMID: 16266757
Malsam J., Satoh A., Pelletier L., Warren G., Golgin tethers define subpopulations of COPI vesicles. Science 307(5712):1095-8 (2005). PMID: 15718469
Kinoshita K., Noetzel T.L., Pelletier L., Mechtler K., Drechsel D.N., Schwager A., Lee M., Raff J.W., Hyman A.A., Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol. 170(7):1047-55 (2005). PMID: 16172205
Kittler R., Pelletier L., Ma C., Poser I., Fischer S., Hyman A.A., Buchholz F., RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells. Proc Natl Acad Sci 102(7):2396-401 (2005). PMID: 15695330
Kittler R., Putz G., Pelletier L., Poser I., Heninger A.K., Drechsel D., Fischer S., Konstantinova I., Habermann B., Grabner H., Yaspo M.L., Himmelbauer H., Korn B., Neugebauer K., Pisabarro M.T., Buchholz F., An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature 432(7020):1036-40 (2004). PMID: 15616564
Pelletier L., Müller-Reichert T., Srayko M., Özlü N., Schlaitz A., Hyman A.A., The C. elegans centrosome during early embryonic development. Book chapter in “Centrosome in development and disease”. Edited by Erich A. Nigg. Published by Wiley (2004). DOI: 10.1002/3527603808.ch12
Dammermann A., Muller-Reichert T., Pelletier L., Habermann B., Desai A., Oegema, K., Centriole assembly requires both centriolar and pericentriolar material proteins. Dev Cell 7(6):815-29 (2004). PMID: 15572125
Pelletier L., Özlü N., Hannak E., Cowan C., Habermann B., Ruer M., Muller-Reichert T. , Hyman A.A., The Caenorhabditis elegans centrosomal protein SPD-2 is required for both pericentriolar material recruitment and centriole duplication. Curr Biol. 14(10):863-73 (2004). PMID: 15186742
Fölsch H., Pypaert M., Maday S., Pelletier L., Mellman I., The AP-1A and AP-1B clathrin adaptor complexes define biochemically and functionally distinct membrane domains. J Cell Biol. 163(2):351-62 (2003). PMID: 14581457
Pelletier L., Stern C.A., Pypaert M., Sheff D., Ngô H.M., Roper N., He C.Y., Hu K., Toomre D., Coppens I., Roos D.S., Joiner K.A., Warren G., Golgi Biogenesis in Toxoplasma gondii. Nature 418(6897):548-52 (2002). PMID: 12152082
*Sheff D.,*Pelletier L., Warren G., Mellman, I., Transferrin receptor recycling in absence of perinuclear recycling endosomes. J Cell Biol. 156(5):797-804 (2002). * Joint-first authors. PMID: 11877458
Pelletier L., Jokitalo, E., Warren G., The Effect of Golgi Depletion on Exocytic Transport. Nat Cell Biol. 2(11):840-846 (2000).PMID: 11056540
